HOUSE -- "The Softer Side" Episode 516 -- Pictured: (l-r) Lisa Edelstein as Cuddy, Robert Sean Leonard as Wilson
In a season 2 episode called “Who’s Your Daddy?” Lisa Cuddy, Gregory House’s boss, considers getting pregnant via a sperm donor. House spends several episodes trying to convince Cuddy not to accept an anonymous sperm donor. (House himself is not sure of his own paternity.) He interviews one of her sperm donors in front of Cuddy to convince her that he’s not the right fit for her baby’s father.